Expresión de búsqueda:
GROWTH DIFFERENTIATION FACTOR 1
Descriptores Encontrados:
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DeCS
Descriptor
Inglés
:
Growth Differentiation Factor 1
Descriptor
Español
:
factor 1 de diferenciación del crecimiento
Descriptor
Portugués
:
Fator 1 de Diferenciação de Crescimento
Sinónimos
Inglés
:
GDF-1
Categoría:
D12.644.276.954.300.100
D12.644.276.954.550.100
D12.776.467.942.300.100
D12.776.467.942.550.100
D23.529.942.300.100
D23.529.942.550.100
Definición
Inglés
:
A
growth
differentiation factor that plays a role in the genesis of left-right asymmetry during
vertebrate
development. Evidence for this role is seen in MICE where loss of
growth differentiation factor 1
function results in right-left
isomerism
of visceral organs. In
HUMANS
heterozygous loss of
growth differentiation factor 1
function has been associated with CONGENITAL HEART DEFECTS and
TRANSPOSITION OF GREAT VESSELS.
Nota Histórica
Inglés
:
2009(2005)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
53139
Identificador Único:
D055452
Ocurrencia en la BVS
:
Similar:
DeCS